Jundishapur Journal of Chronic Disease Care

Published by: Kowsar

The Modifying Impact of Long-Term Endurance Training on Inflammatory Cytokine IL-1B Level and VO2max in Premenopausal Women with Abdominal Obesity

Laleh Behboudi 1 and Mojtaba Eizadi 2 , *
Authors Information
1 Department of Exercise Physiology, Islamshahr Branch, Islamic Azad University, Tehran, Iran
2 Department of Exercise Physiology, Saveh Branch, Islamic Azad University, Saveh, Iran
Article information
  • Jundishapur Journal of Chronic Disease Care: October 2017, 6 (4); e57180
  • Published Online: October 31, 2017
  • Article Type: Research Article
  • Received: June 30, 2017
  • Revised: September 21, 2017
  • Accepted: October 2, 2017
  • DOI: 10.5812/jjcdc.57180

To Cite: Behboudi L, Eizadi M. The Modifying Impact of Long-Term Endurance Training on Inflammatory Cytokine IL-1B Level and VO2max in Premenopausal Women with Abdominal Obesity, Jundishapur J Chronic Dis Care. 2017 ; 6(4):e57180. doi: 10.5812/jjcdc.57180.

Copyright © 2017, Jundishapur Journal of Chronic Disease Care. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Vinagre I, Sanchez-Quesada JL, Sanchez-Hernandez J, Santos D, Ordonez-Llanos J, De Leiva A, et al. Inflammatory biomarkers in type 2 diabetic patients: effect of glycemic control and impact of LDL subfraction phenotype. Cardiovasc Diabetol. 2014;13:34. doi: 10.1186/1475-2840-13-34. [PubMed: 24495560].
  • 2. Pereira GB, Tibana RA, Navalta J, Sousa NM, Cordova C, Souza VC, et al. Acute effects of resistance training on cytokines and osteoprotegerin in women with metabolic syndrome. Clin Physiol Funct Imaging. 2013;33(2):122-30. doi: 10.1111/cpf.12004. [PubMed: 23383690].
  • 3. Praveen G, Srinivasa BS. Profile and clinical features of HIV positive patients attending integrated counseling and testing centre in a medical college hospital of Hassan, Karnataka. Int J Med Sci Public Health. 2013;2:300-4.
  • 4. Pirola L, Ferraz JC. Role of pro- and anti-inflammatory phenomena in the physiopathology of type 2 diabetes and obesity. World J Biol Chem. 2017;8(2):120-8. doi: 10.4331/wjbc.v8.i2.120. [PubMed: 28588755].
  • 5. Liu C, Hart RP, Liu XJ, Clevenger W, Maki RA, De Souza EB. Cloning and characterization of an alternatively processed human type II interleukin-1 receptor mRNA. J Biol Chem. 1996;271(34):20965-72. doi: 10.1074/jbc.271.34.20965.
  • 6. Peiro C, Lorenzo O, Carraro R, Sanchez Ferrer CF. IL-1beta inhibition in cardiovascular complications associated to diabetes mellitus. Front Pharmacol. 2017;8:363. doi: 10.3389/fphar.2017.00363. [PubMed: 28659798].
  • 7. Ghomari Boukhatem H, Bouchouicha A, Mekki K, Chenni K, Belhadj M, Bouchenak M. Blood pressure, dyslipidemia and inflammatory factors are related to body mass index in scholar adolescents. Arch Med Sci. 2017;1:46-52. doi: 10.5114/aoms.2017.64713.
  • 8. Mehta R, Neupane A, Wang L, Goodman Z, Baranova A, Younossi ZM. Expression of NALPs in adipose and the fibrotic progression of non-alcoholic fatty liver disease in obese subjects. BMC Gastroenterol. 2014;14:208. doi: 10.1186/s12876-014-0208-8. [PubMed: 25512222].
  • 9. Cieslak M, Wojtczak A, Cieslak M. Role of pro-inflammatory cytokines of pancreatic islets and prospects of elaboration of new methods for the diabetes treatment. Acta Biochim Pol. 2015;62(1):15-21. [PubMed: 25781159].
  • 10. Bahrami A, Saremi A. Effect of caloric restriction with or without aerobic training on body composition, blood lipid profile, insulin resistance, and inflammatory marker in middle age obese overweight men. Arak Med Univ J. 2011;14(3):11-9.
  • 11. Babbitt DM, Diaz KM, Feairheller DL, Sturgeon KM, Perkins AM, Veerabhadrappa P, et al. Endothelial activation microparticles and inflammation status improve with exercise training in african Americans. Int J Hypertens. 2013;2013:1-8. doi: 10.1155/2013/538017.
  • 12. Balducci S, Zanuso S, Nicolucci A, Fernando F, Cavallo S, Cardelli P, et al. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss. Nutr Metab Cardiovasc Dis. 2010;20(8):608-17. doi: 10.1016/j.numecd.2009.04.015. [PubMed: 19695853].
  • 13. Lopes WA, Leite N, da Silva LR, Brunelli DT, Gaspari AF, Radominski RB, et al. Effects of 12 weeks of combined training without caloric restriction on inflammatory markers in overweight girls. J Sports Sci. 2016;34(20):1902-12. doi: 10.1080/02640414.2016.1142107. [PubMed: 26852885].
  • 14. Oh EG, Bang SY, Kim SH, Hyun SS, Chu SH, Jeon JY, et al. Therapeutic lifestyle modification program reduces plasma levels of the chemokines CRP and MCP-1 in subjects with metabolic syndrome. Biol Res Nurs. 2013;15(1):48-55. doi: 10.1177/1099800411416637. [PubMed: 21859748].
  • 15. Chen YY, Chiang J, Chen YJ, Chen KT, Yang RS, Lin JG. Cycling and Tai Chi Chuan exercises exert greater immunomodulatory effect on surface antigen expression of human hepatitis B virus. Chin Med J (Engl). 2008;121(21):2172-9. [PubMed: 19080180].
  • 16. Sheikholeslami vatani D, ahmadi S, mojtahedi H, marandi M, ahmadi dehrashid K, faraji H, et al. Influence of different intensities of resistance exercise on inflammatory markers in young healthy men. Int J Endocrinol Metab. 2011;12(6):618-25.
  • 17. Azizbigi BK, Atashak S, Etemad Z, Khalilzadeh K, Yektayar M. The effect of resistance training with moderate and high intensity on the change of plasma antioxidant n inflammation markers in healthy men. Sci J Kurdistan Univ Med Sci. 2013;18(4):1-7.
  • 18. Mehrabani J, Damirchi A, Rahmaninia F. The effect of two aerobic training intensities on lipocalin-2, interleukin-2 levels and insulin resistance index in sedentary obese men. Exerc Physiol. 2014;21:95-108.
  • 19. Eizadi M, Sokhanguei Y, Eghdami A, Banaeifar A. Effect of aerobic exercise on pancreas beta-cells function in adult obese males. J Birjand Univ Med Sci. 2014;21(2):203-10.
  • 20. Baum M, Klopping-Menke K, Muller-Steinhardt M, Liesen H, Kirchner H. Increased concentrations of interleukin 1-beta in whole blood cultures supernatants after 12 weeks of moderate endurance exercise. Eur J Appl Physiol Occup Physiol. 1999;79(6):500-3. [PubMed: 10344459].
  • 21. Eisanezhad A, Hassan Saraf Z, Mahdavi M, Ghakhanlu R. The effect of aerobic exercise training on serum levels of tnf-Α, Il - 1β, Il-6 and Hsp70 in Rats. J Sport Biosci. 2013;4(15):91-106.
  • 22. Martin-Cordero L, Garcia JJ, Giraldo E, De la Fuente M, Manso R, Ortega E. Influence of exercise on the circulating levels and macrophage production of IL-1beta and IFNgamma affected by metabolic syndrome: an obese Zucker rat experimental animal model. Eur J Appl Physiol. 2009;107(5):535-43. doi: 10.1007/s00421-009-1140-4. [PubMed: 19688220].
  • 23. Codoner Franch P, Tavarez Alonso S, Porcar Almela M, Navarro Solera M, Arilla Codoner A, Alonso Iglesias E. Plasma resistin levels are associated with homocysteine, endothelial activation, and nitrosative stress in obese youths. Clin Biochem. 2014;47(1-2):44-8. doi: 10.1016/j.clinbiochem.2013.10.021. [PubMed: 24183883].
  • 24. Tonstad S, Cowan JL. C-reactive protein as a predictor of disease in smokers and former smokers: a review. Int J Clin Pract. 2009;63(11):1634-41. doi: 10.1111/j.1742-1241.2009.02179.x. [PubMed: 19732183].
  • 25. Khan MA. Inflammation signals airway smooth muscle cell proliferation in asthma pathogenesis. Multidiscip Respir Med. 2013;8(1):11. doi: 10.1186/2049-6958-8-11. [PubMed: 23388501].
  • 26. Das UN. Anti inflammatory nature of exercise. Nutrition. 2004;20(3):323-6. doi: 10.1016/j.nut.2003.11.017. [PubMed: 14990277].
  • 27. Ho TP, Zhao X, Courville AB, Linderman JD, Smith S, Sebring N, et al. Effects of a 12-month moderate weight loss intervention on insulin sensitivity and inflammation status in nondiabetic overweight and obese subjects. Horm Metab Res. 2015;47(4):289-96. doi: 10.1055/s-0034-1382011. [PubMed: 24977656].
  • 28. Donges CE, Duffield R, Guelfi KJ, Smith GC, Adams DR, Edge JA. Comparative effects of single-mode vs. duration-matched concurrent exercise training on body composition, low-grade inflammation, and glucose regulation in sedentary, overweight, middle-aged men. Appl Physiol Nutr Metab. 2013;38(7):779-88. doi: 10.1139/apnm-2012-0443. [PubMed: 23980737].
  • 29. Ordonez FJ, Rosety MA, Camacho A, Rosety I, Diaz AJ, Fornieles G, et al. Aerobic training improved low-grade inflammation in obese women with intellectual disability. J Intellect Disabil Res. 2014;58(6):583-90. doi: 10.1111/jir.12056. [PubMed: 23742222].
  • 30. Bijeh N, Abbasian S. The Effect of intensity of aerobic training and dietary pattern changing on interleukin-1β and resistance insulin indexes in non-active obese subjects. Arak Med Univ J. 2013;16(7):1-13.
  • 31. Varady KA, Tussing L, Bhutani S, Braunschweig CL. Degree of weight loss required to improve adipokine concentrations and decrease fat cell size in severely obese women. Metabolism. 2009;58(8):1096-101. doi: 10.1016/j.metabol.2009.04.010. [PubMed: 19477470].
  • 32. Sheu WH, Chang TM, Lee WJ, Ou HC, Wu CM, Tseng LN, et al. Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Obesity (Silver Spring). 2008;16(5):1033-8. doi: 10.1038/oby.2008.37. [PubMed: 18356846].
  • 33. Gielen S, Adams V, Mobius-Winkler S, Linke A, Erbs S, Yu J, et al. Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure. J Am Coll Cardiol. 2003;42(5):861-8. [PubMed: 12957433].
  • 34. Ghanbari-Niaki A. Ghrelin and glucoregulatory hormone responses to a single circuit resistance exercise in male college students. Clin Biochem. 2006;39(10):966-70. doi: 10.1016/j.clinbiochem.2006.05.009. [PubMed: 16979150].
  • 35. Brunelli DT, Chacon-Mikahil MP, Gaspari AF, Lopes WA, Bonganha V, Bonfante IL, et al. Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men. Med Sci Sports Exerc. 2015;47(10):2207-15. doi: 10.1249/MSS.0000000000000658. [PubMed: 26378946].
  • 36. Stavropoulos-Kalinoglou A, Metsios GS, Veldhuijzen van Zanten JJ, Nightingale P, Kitas GD, Koutedakis Y. Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis. Ann Rheum Dis. 2013;72(11):1819-25. doi: 10.1136/annrheumdis-2012-202075. [PubMed: 23155222].
  • 37. Karch I, Olszowska M, Tomkiewicz Pajak L, Drapisz S, Luszczak J, Podolec P. The effect of physical activity on serum levels of selected biomarkers of atherosclerosis. Kardiol Pol. 2013;71(1):55-60. [PubMed: 23348535].
  • 38. Smart NA, Larsen AI, Le Maitre JP, Ferraz AS. Effect of exercise training on interleukin-6, tumour necrosis factor alpha and functional capacity in heart failure. Cardiol Res Pract. 2011;2011:532620. doi: 10.4061/2011/532620. [PubMed: 21403878].
  • 39. Milani RV, Lavie CJ, Mehra MR. Reduction in C-reactive protein through cardiac rehabilitation and exercise training. J Am Coll Cardiol. 2004;43(6):1056-61. doi: 10.1016/j.jacc.2003.10.041. [PubMed: 15028366].
  • 40. Gomez-Merino D, Drogou C, Guezennec CY, Chennaoui M. Effects of chronic exercise on cytokine production in white adipose tissue and skeletal muscle of rats. Cytokine. 2007;40(1):23-9. doi: 10.1016/j.cyto.2007.07.188. [PubMed: 17826174].
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