Jundishapur Journal of Chronic Disease Care

Published by: Kowsar

Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran

Alireza Sanchooli 1 , 2 , 3 , * , Manoochehr Makvandi 1 , 2 , Niloofar Nisi 1 , 2 and Rahil Nahid Samiei 1 , 2
Authors Information
1 Infectious and Tropical Disease Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
2 Virology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
3 Department of Genomics and Genetic Engineering, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, IR Iran
Article information
  • Jundishapur Journal of Chronic Disease Care: April 2018, 7 (2); e66417
  • Published Online: April 30, 2018
  • Article Type: Research Article
  • Received: January 17, 2018
  • Revised: March 14, 2018
  • Accepted: April 24, 2018
  • DOI: 10.5812/jjcdc.66417

To Cite: Sanchooli A, Makvandi M, Nisi N, Samiei R N. Prevalence of Hepatitis G Virus and Co-Infection with Hepatitis B Virus and Hepatitis C Virus Among Hemodialysis Patients in Ahvaz, Iran, Jundishapur J Chronic Dis Care. 2018 ; 7(2):e66417. doi: 10.5812/jjcdc.66417.

Copyright © 2018, Jundishapur Journal of Chronic Disease Care. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Ramos Filho R, Carneiro MA, Teles SA, Dias MA, Cardoso DD, Lampe E, et al. GB virus C/hepatitis G virus infection in dialysis patients and kidney transplant recipients in Central Brazil. Mem Inst Oswaldo Cruz. 2004;99(6):639-43. [PubMed: 15558178].
  • 2. Soleiman-Meigooni S, Asgari A, Hoseini-Shokouh SJ, Rajabi J, Kazemi-Galougahi MH, Moshtaghi M. Association between Hepatitis G and Unknown Chronic Hepatitis. Electron Physician. 2015;7(1):985-9. doi: 10.14661/2015.985-989. [PubMed: 26052409].
  • 3. Simons JN, Leary TP, Dawson GJ, Pilot-Matias TJ, Muerhoff AS, Schlauder GG, et al. Isolation of novel virus-like sequences associated with human hepatitis. Nat Med. 1995;1(6):564-9. doi: 10.1038/nm0695-564. [PubMed: 7585124].
  • 4. Linnen J, Wages JJ, Zhang-Keck ZY, Fry KE, Krawczynski KZ, Alter H, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science. 1996;271(5248):505-8. doi: 10.1126/science.271.5248.505. [PubMed: 8560265].
  • 5. Alvarado-Mora MV, Botelho L, Nishiya A, Neto RA, Gomes-Gouvea MS, Gutierrez MF, et al. Frequency and genotypic distribution of GB virus C (GBV-C) among Colombian population with Hepatitis B (HBV) or Hepatitis C (HCV) infection. Virol J. 2011;8:345. doi: 10.1186/1743-422X-8-345. [PubMed: 21745373].
  • 6. Bhattarai N, Stapleton JT. GB virus C: the good boy virus? Trends Microbiol. 2012;20(3):124-30. doi: 10.1016/j.tim.2012.01.004. [PubMed: 22325031].
  • 7. Yang JF, Dai CY, Chuang WL, Lin WY, Lin ZY, Chen SC, et al. Prevalence and clinical significance of HGV/GBV-C infection in patients with chronic hepatitis B or C. Jpn J Infect Dis. 2006;59(1):25-30. [PubMed: 16495630].
  • 8. Ozdarendeli A, Toroman ZA, Kalkan A, Kilic SS, Ozden M, Doymaz MZ. Prevalence and genotypes of hepatitis G virus among hemodialysis patients in Eastern Anatolia, Turkey. Med Princ Pract. 2005;14(2):102-6. doi: 10.1159/000083920. [PubMed: 15785102].
  • 9. Laskus T, Radkowski M, Wang LF, Vargas H, Rakela J. Lack of evidence for hepatitis G virus replication in the livers of patients coinfected with hepatitis C and G viruses. J Virol. 1997;71(10):7804-6. [PubMed: 9311866].
  • 10. Chang CM, Stapleton JT, Klinzman D, McLinden JH, Purdue MP, Katki HA, et al. GBV-C infection and risk of NHL among U.S. adults. Cancer Res. 2014;74(19):5553-60. doi: 10.1158/0008-5472.CAN-14-0209. [PubMed: 25115299].
  • 11. Handajani R, Lusida MI, Suryohudoyo P, Adi P, Setiawan PB.Soetjipto, et al. Prevalence of GB virus C/Hepatitis G virus infection among various populations in Surabaya, Indonesia, and identification of novel groups of sequence variants. J Clin Microbiol. 2000;38(2):662-8. [PubMed: 10655364].
  • 12. Hassan H, Bastani B. Hepatitis G virus infection among hemodialysis patients: true infection or innocent bystander? Semin Dial. 2000;13(2):108-11. doi: 10.1046/j.1525-139x.2000.00035.x. [PubMed: 10795114].
  • 13. Stapleton JT, Foung S, Muerhoff AS, Bukh J, Simmonds P. The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae. J Gen Virol. 2011;92(Pt 2):233-46. doi: 10.1099/vir.0.027490-0. [PubMed: 21084497].
  • 14. Masuko K, Mitsui T, Iwano K, Yamazaki C, Okuda K, Meguro T, et al. Infection with hepatitis GB virus C in patients on maintenance hemodialysis. N Engl J Med. 1996;334(23):1485-90. doi: 10.1056/NEJM199606063342301. [PubMed: 8618602].
  • 15. de Lamballerie X, Charrel RN, Dussol B. Hepatitis GB virus C in patients on hemodialysis. N Engl J Med. 1996;334(23):1549. doi: 10.1056/NEJM199606063342319. [PubMed: 8618624].
  • 16. Feucht HH, Zollner B, Polywka S, Knodler B, Schroter M, Nolte H, et al. Prevalence of hepatitis G viremia among healthy subjects, individuals with liver disease, and persons at risk for parenteral transmission. J Clin Microbiol. 1997;35(3):767-8. [PubMed: 9041431].
  • 17. Di Bisceglie AM. Hepatitis G virus infection: a work in progress. Ann Intern Med. 1996;125(9):772-3. [PubMed: 8929013].
  • 18. Berzsenyi MD, Bowden DS, Roberts SK. GB virus C: insights into co-infection. J Clin Virol. 2005;33(4):257-66. doi: 10.1016/j.jcv.2005.04.002. [PubMed: 15922655].
  • 19. Samarbaf-Zadeh AR, Makvandi M, Hamadi A, Kaydani GA, Absalan A, Afrough P, et al. Prevalence of Hepatitis G Virus Among Hemodialysis and Kidney Transplant Patients in Khuzestan Province, Iran. Jundishapur J Microbiol. 2015;8(5). e20834. doi: 10.5812/jjm.20834. [PubMed: 26060569].
  • 20. Kelishadi M, Mojerloo M, Moradi A, Bazouri M, Hashemi P, Samadi S, et al. GB virus C Viremia and Anti-E2 Antibody Response Among Hemodialysis Patients in Gorgan, Iran. Jundishapur J Microbiol. 2014;7(11). e13122. doi: 10.5812/jjm.13122. [PubMed: 25774276].
  • 21. Davod J, Javanmard D, Makvandi M, Hajiani E, Khalafkhany D, Samarbaf Zadeh AR. Hepatitis G virus (HGV), its prevalence and genotypes in patients with hepatitis B & C in Ahvaz, Southwest Iran. Turk J Med Sci. 2013;43:474-8. doi: 10.3906/sag-1203-55.
  • 22. De Filippi F, Lampertico P, Soffredini R, Rumi MG, Lunghi G, Aroldi A, et al. High prevalence, low pathogenicity of hepatitis G virus in kidney transplant recipients. Dig Liver Dis. 2001;33(6):477-9. doi: 10.1016/S1590-8658(01)80025-6. [PubMed: 11572574].
  • 23. Heringlake S, Osterkamp S, Trautwein C, Tillmann HL, Boker K, Muerhoff S, et al. Association between fulminant hepatic failure and a strain of GBV virus C. Lancet. 1996;348(9042):1626-9. doi: 10.1016/S0140-6736(96)04413-3. [PubMed: 8961994].
  • 24. Watanabe MA, Milanezi CM, Silva WJ, de Lucena Angulo I, Santis G, Kashima S, et al. Molecular investigation of GB virus C RNA in hemodialysis and thalassemics patients from Brazil. Ren Fail. 2003;25(1):67-75. doi: 10.1081/JDI-120017469. [PubMed: 12617334].
  • 25. Okuda M, Hino K, Korenaga M, Yamaguchi Y, Kao Y, Mukaide M. GB virus C/hepatic G viremia and antibody response to the E2 protein of hepatitis G virus in hemodialysis patients. J Clin Gastroenterol. 2000;30:425-8.
  • 26. Kao JH, Huang CH, Chen W, Tsai TJ, Lee SH, Hung KY, et al. GB virus C infection in hemodialysis patients: molecular evidence for nosocomial transmission. J Infect Dis. 1999;180(1):191-4. doi: 10.1086/314850. [PubMed: 10353878].
  • 27. Hosseini-Moghaddam SM, Keyvani H, Samadi M, Alavian SM, Mahdavimazdeh M, Daneshvar S, et al. GB virus type C infection in hemodialysis patients considering co-infection with hepatitis C virus. J Med Virol. 2008;80(7):1260-3. doi: 10.1002/jmv.21161. [PubMed: 18461616].
  • 28. Ziaee M, Zarban A, Malekinejad P, Akhbary H. Evaluation of HGV viremia prevalence and its co-infection with HBV, HCV, HIV and HTLV-1 in hemophilic patients of Southern Khorassan, Iran. Hepat Mon. 2007;7(1):11-4.
  • 29. Kafi-Abad SA, Samiei S, Talebian A, Maghsudloo M, Gharehbaghian A. Hepatitis G virus infection in Iranian blood donors and high-risk groups. Hepat Mon. 2009;9:282-6.
  • 30. Dadmanesh M, Hosseinzadeh M, Keyvani H, Ghorban K, Rahimi M, Hosseinzadeh M, et al. Evaluation of prevalence and risk factors of hepatitis g virus infection among hemodialysis patients referred to Iranian army hospitals in tehran during 2012-2013. Hepat Mon. 2015;15(1). e18322. doi: 10.5812/hepatmon.18322. [PubMed: 25741370].
  • 31. Kargar Kheirabad A, Bahri F, Kargar M, Ghasemzadeh I. Hepatitis C and G Virus Infection Prevalence Among Hemodialysis Patients and Associated Risk Factors in the Hormozgan Province of Southern Iran. Hepat Mon. 2016;16(10). e40375. doi: 10.5812/hepatmon.40375. [PubMed: 27882069].
  • 32. Samadi M, Keyvani H, Moghaddam SMH. Prevalence and risk factors of the hepatitis G (HGV) infection in hemodialysis patients. Iran J Clin Infect Dis. 2008;3(1):7-11.
  • 33. Mohsenzadeh M. Molecular evaluation of hepatitis G virus and hepatitis C virus in patients with chronic renal failure in Iran. Afr J Microbiol Res. 2012;6(33):6257-61. doi: 10.5897/ajmr12.575.
  • 34. Rinonce HT, Yano Y, Utsumi T, Heriyanto DS, Anggorowati N, Widasari DI, et al. Prevalence and genotypic distribution of GB virus C and torque teno virus among patients undergoing hemodialysis. Mol Med Rep. 2017;15(5):2843-52. doi: 10.3892/mmr.2017.6281.
  • 35. Ben Dhifallah I, Ayouni K, Chouiha A, Sadraoui A, Hogga N, Hammami W, et al. Genotype Distribution and Prevalence of Human Pegivirus among High-Risk Populations in Tunisia. Intervirology. 2016;59(3):170-8. doi: 10.1159/000454810. [PubMed: 28132064].
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