Jundishapur Journal of Chronic Disease Care

Published by: Kowsar

Comparative Study of the Effect of Licorice Root Extract Mouthwash and Combined Mouthwash on the Incidence and Severity of Chemotherapy-Induced Mucositis Symptoms in Colon Cancer Patients Admitted to Intensive Care Units

Amin Sattari 1 , Abdolali Shariati ORCID 2 , * , Nader Shakiba Maram 3 , Ali Ehsanpour 4 and Elham Maraghi 5
Authors Information
1 Nursing and Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Nursing Care Research Center in Chronic Diseases, Nursing and Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Assistant Professor of Pharmaceutics, Department of Pharmaceutics, School of Pharmacy, Nanotechnology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4 Assistant Professor, Division of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
5 Assistant Professor of Biostatistics, Department of Biostatistics and Epidemiology, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Article information
  • Jundishapur Journal of Chronic Disease Care: July 31, 2019, 8 (3); e88641
  • Published Online: June 3, 2019
  • Article Type: Research Article
  • Received: January 2, 2019
  • Revised: March 16, 2019
  • Accepted: April 30, 2019
  • DOI: 10.5812/jjcdc.88641

To Cite: Sattari A, Shariati A, Shakiba Maram N, Ehsanpour A, Maraghi E. Comparative Study of the Effect of Licorice Root Extract Mouthwash and Combined Mouthwash on the Incidence and Severity of Chemotherapy-Induced Mucositis Symptoms in Colon Cancer Patients Admitted to Intensive Care Units, Jundishapur J Chronic Dis Care. 2019 ; 8(3):e88641. doi: 10.5812/jjcdc.88641.

Copyright © 2019, Jundishapur Journal of Chronic Disease Care. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Santo EARDE, Gaíva MAM, Espinosa MM, Barbosa DA, Belasco AGS. Taking care of children with cancer: Evaluation of the caregivers' burden and quality of life. Rev Lat-Am Enferm. 2011;19(3):515-22. doi: 10.1590/s0104-11692011000300010.
  • 2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90. doi: 10.3322/caac.20107. [PubMed: 21296855].
  • 3. Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev. 2010;36(4):277-85. doi: 10.1016/j.ctrv.2010.02.003. [PubMed: 20231056].
  • 4. Siegel R, Naishadham D, Jemal A. Cancer statistics for Hispanics/Latinos, 2012. CA Cancer J Clin. 2012;62(5):283-98. doi: 10.3322/caac.21153. [PubMed: 22987332].
  • 5. Torre LA, Sauer AM, Chen MS, Jr, Kagawa-Singer M, Jemal A, Siegel RL. Cancer statistics for Asian Americans, Native Hawaiians, and Pacific Islanders, 2016: Converging incidence in males and females. CA Cancer J Clin. 2016;66(3):182-202. doi: 10.3322/caac.21335. [PubMed: 26766789]. [PubMed Central: PMC5325676].
  • 6. Pourhoseingholi MA. Epidemiology and burden of colorectal cancer in Asia-Pacific region: what shall we do now? Transl Gastrointest Cancer. 2014;3(4):169-73. doi: 10.3978/j.issn.2224-4778.2014.08.10.
  • 7. National Institutes of Health. Support for people with cancer chemotherapy and you. National Cancer Institute U.S. Department of Health and Human Services [updated 2011]. 2007. Available from: www.cancer.gov/cancertopics/chemotherapy-and-you.pdf.
  • 8. Libutti SK, Saltz LB, Willett CG. Cancer of the colon. In: Devita VT, Lawrence TS, Rosenberg SA, editors. Cancer principles & practice of oncology. 9th ed. Philadelphia: Lippincott Williams & Wilkins; 2011. p. 1084-126.
  • 9. Munro CL, Grap MJ. Oral health and care in the intensive care unit: state of the science. Am J Crit Care. 2004;13(1):25-33. discussion 34. [PubMed: 14735645].
  • 10. Johnstone L, Spence D, Koziol-McClain J. Oral hygiene care in the pediatric intensive care unit: Practice recommendations. Pediatr Nurs. 2010;36(2):85-96. quiz 97. [PubMed: 20476510].
  • 11. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology. St. Louis, MO: Saunders/Elsevier; 2009.
  • 12. Jones H, Newton JT, Bower EJ. A survey of the oral care practices of intensive care nurses. Intensive Crit Care Nurs. 2004;20(2):69-76. doi: 10.1016/j.iccn.2004.01.004. [PubMed: 15072774].
  • 13. Dehabadi F, Badiee Z, Parisan I. [The prevalence of oral mucositis caused by chemotherapy and its risk factors in children with cancer who were referred to hematology and oncology wards of Doctor Sheikh Hospital in 2014]. Med J Mashhad Univ Med Sci. 2016;58(10):578-89. Persian.
  • 14. Parsapour P, Shahsiah S, Alavinejad P, Iravani S, Mofatteh Z, Pedram P. [The effect of vitamin e therapy on post chemotherapy mucositis in leukemic patients]. J Isfahan Dent Sch. 2018;14(1):56-63. Persian.
  • 15. Al-Dasooqi N, Sonis ST, Bowen JM, Bateman E, Blijlevens N, Gibson RJ, et al. Emerging evidence on the pathobiology of mucositis. Support Care Cancer. 2013;21(7):2075-83. doi: 10.1007/s00520-013-1810-y. [PubMed: 23604521].
  • 16. Ashktorab T, Yazdani Z, Mojab F, Alavi Majd H, Madani H. [Effect of peppermint mouthwash on the prevention of chemotherapy-induced oral mucositis]. J Semnan Med Sci Univ. 2010;12(1):8-13. Persian.
  • 17. Akhavan Karbasi MH, Forat Yazdi M, Ahadian H, Jalili Sadrabad M. [Evaluating baremoom mouthwash efficacy in treatment of chemotherapy-induced mucositis]. J Shahid Sadoughi Univ Med Sci. 2016;23(12):1202-14. Persian.
  • 18. Bensadoun RJ, Nair RG. Low-level laser therapy in the prevention and treatment of cancer therapy-induced mucositis: 2012 state of the art based on literature review and meta-analysis. Curr Opin Oncol. 2012;24(4):363-70. doi: 10.1097/CCO.0b013e328352eaa3. [PubMed: 22450151].
  • 19. Bahramnezhad F, Bassampour S, Larizadeh MH, Mohammadi E, Haghani H, Yari M. [Comparison of honey and chamomile mouthwash in intensity stomatitis among patients with head and neck radiotherapy]. Complement Med J Faculty Nurs Midwifery. 2013;3(2):429-40. Persian.
  • 20. Hadadian F, fayazi S, Ghorbani A, Falah H, Latifi SM. [The effect of trancscutaneus electrical acupoint stimulation (TEAS) on fatigue reduction in hemodialysis patients]. J Kermanshah Univ Med Sci. 2011;15(3). Persian. e79354.
  • 21. Khoshnam SE, Farzaneh M, Bahaoddini A. [Review of the phytochemical, pharmacological and physiological properties of Licorice (Glycyrrhizaglabra)]. J Clin Exc. 2015;4(1):71-56. Persian.
  • 22. Soltani N, Karami R, Ranjbar M. The interaction of salicylic acid and cold stress on antioxidant enzyme activities in licorice (Glycyrrhiza glabra). J Herbal Drugs. 2011;2(1):7-13.
  • 23. Amani M, Sotudeh-Gharebagh R, Mostoufiand N, Motahhari Kashani HA. Optimal extraction of glycyrrhetinic acid froml icorice root. J Food Tech. 2005;3(4):576-80.
  • 24. Das D, Agarwal SK, Chandola HM. Protective effect of Yashtimadhu (Glycyrrhiza glabra) against side effects of radiation/chemotherapy in head and neck malignancies. Ayu. 2011;32(2):196-9. doi: 10.4103/0974-8520.92579. [PubMed: 22408302]. [PubMed Central: PMC3296340].
  • 25. Aghamohammadi A, Moslemi D, Akbari J, Ghasemi A, Azadbakht M, Asgharpour A, et al. The effectiveness of Zataria extract mouthwash for the management of radiation-induced oral mucositis in patients: a randomized placebo-controlled double-blind study. Clin Oral Investig. 2018;22(6):2263-72. doi: 10.1007/s00784-017-2324-7. [PubMed: 29313134].
  • 26. Ghoreishi Z, Shidfar F, Iravani M, Esfahani A, Ghavamzadeh A. Effect of vitamin E on chemotherapy-induced mucositis and neutropenia in leukemic patients undergoing bone marrow transplantation. Asia-pac j clin onco. 2007;3(3):113-8. doi: 10.1111/j.1743-7563.2007.00111.x.
  • 27. Kong M, Hwang DS, Yoon SW, Kim J. The effect of clove-based herbal mouthwash on radiation-induced oral mucositis in patients with head and neck cancer: a single-blind randomized preliminary study. Onco Targets Ther. 2016;9:4533-8. doi: 10.2147/OTT.S108769. [PubMed: 27524909]. [PubMed Central: PMC4966496].
  • 28. Stokman MA, Burlage FR, Spijkervet FK. The effect of a calcium phosphate mouth rinse on (chemo) radiation induced oral mucositis in head and neck cancer patients: a prospective study. Int J Dent Hyg. 2012;10(3):175-80. doi: 10.1111/j.1601-5037.2012.00574.x. [PubMed: 23046006].
  • 29. Wong KH, Kuciejewska A, Sharabiani MTA, Ng-Cheng-Hin B, Hoy S, Hurley T, et al. A randomised controlled trial of Caphosol mouthwash in management of radiation-induced mucositis in head and neck cancer. Radiother Oncol. 2017;122(2):207-11. doi: 10.1016/j.radonc.2016.06.015. [PubMed: 27393218]. [PubMed Central: PMC6157713].
  • 30. Najafi S, Koujan SE, Manifar S, Kharazifard MJ, Kidi S, Hajheidary S. Preventive effect of Glycyrrhiza glabra extract on oral mucositis in patients under head and neck radiotherapy: A randomized clinical trial. J Dent (Tehran). 2017;14(5):267-74. [PubMed: 29296112]. [PubMed Central: PMC5748454].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments