Evaluation of standardized ginseng extract Panax (G115 ®) effect on fasting blood glucose levels, glycated hemoglobin and lipid profile in patients with diabetes type 2

AUTHORS

Seyed Ahmad Hosseini 1 , Ali Ehsanpour 2 , Mehdi Asgari 3 , Reza Malihi 1 , *

1 Department of Nutrition, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Department of Internal Medicine, Razi Hospital, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran

3 Department of Surgery, Razi Hospital, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran

How to Cite: Hosseini S A, Ehsanpour A, Asgari M, Malihi R. Evaluation of standardized ginseng extract Panax (G115 ®) effect on fasting blood glucose levels, glycated hemoglobin and lipid profile in patients with diabetes type 2, Jundishapur J Chronic Dis Care. 2013 ; 2(3):e93793.

ARTICLE INFORMATION

Jundishapur Journal of Chronic Disease Care: 2 (3); e93793
Published Online: July 30, 2013
Article Type: Research Article
Received: May 15, 2019
Accepted: January 11, 2013

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Abstract

Introduction: Despite enormous efforts to search for cure, diabetes mellitus still remains as a formidable challenge for public health. This project was designed to evaluate effect of standardized ginseng extract Panaxs (G115®) on fasting blood glucose levels, glycated hemoglobin and lipid profiles in patients with diabetes type 2.

Materials & Methods: In this randomized, double blind placebo controlled clinical trial, 30 patients with type 2 diabetes were contributed. They were divided into two groups (n=15 each), the randomized and placebo groups, the former received300 mg/day G115 and placebo received300 mg/d wheat flour. FBS, HbA1c and lipid profile were determined at baseline and at the end of study. SPSS version 18.0 (SPSS Inc, Chicago, IL, USA) was used for data analysis. Independent and paired samples T-test was applied for comparison.

Results: Subjects randomized to G115, as compared to the placebo group, had a significant decrease in HbA1c (t= -2.593,p=0.015)) and FBS levels (t=-2.13,p=0.042). There was no improvement lipid profiles of subjects randomized to G115, compared to controls.

Conclusion: Results of this study suggest that G115 supplementation in subjects with type 2 diabetes may improve glucose control but it has no significantly effect on lipid profiles.

Keywords

Panax ginseng Fasting blood glucose Glycated hemoglobin Lipid profiles

© 2013, Jundishapur Journal of Chronic Disease Care. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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